I am a medical doctor, I might even be your medical doctor, but this review is not intended to replace the advice and guidance of a medical professional. So, with that out of the way, TL, DR: Buy the book. Go to page 319. Purchase the supplements from a reputable source. Start looking and feeling better.
Full disclosure. I know the author, but I purchased my own copy of the book and I have not been coached on what to say.
For many people, who just want to know what to do, the first line of the review tells you all you need to know. But for anyone who is interested in longevity research, healthy aging, or "anti-aging" medicine, what the author has done is looked at the currently available research and broken it down into simple, easy to understand language. She has done all the heavy mental lifting, sifting through hundreds of scientific papers and reading the primary literature to synthesize her theory of aging. Once you have a theory, now you have a framework with which to attack the problem. That is where the bulk of the book spends its time. Is her theory of aging entirely correct? I don't know, and neither do you or anyone else, at least not yet. It is more correct than what we understood 10 years ago. We will probably shake our heads at how wrong we were 50 years from now (with any luck). This book is a really great educated guess. I would argue that there are other great supplements that should have made the list such as all the forms of Vitamin E, which are great anti-oxidants and anti-inflammatory compounds.
What this book does is even the playing field. Millionaires and Billionaires spend hundreds of thousands of dollars to help them stay in great physical and mental condition. They create companies that are looking for the next best thing, products or proprietary compounds to help us look and feel better. (e.g. Ambrosia) Unless you have 7 figures in your bank account, you can't afford what they can get. But is it necessary to spend that much? This book will argue convincingly the answer is No.
The author starts with the necessary framework to understand what a basic biochemistry text doesn't cover. These critical pathways discussed have only recently been elucidated and, admittedly, our knowledge is still incomplete. Nevertheless, a partially complete map will start us further on the path than waiting for a perfect map. All of the supplements are easily available, relatively inexpensive and have clear literature supporting their use. There are clinical trials currently ongoing to show metformin is an anti-aging drug! The price for that off patent medicationwill really go up if shown to work!
Will there be special circumstances and health conditions of a specific patient that would be a contraindication to one or more of these compounds? Yes. This book is a description, not a prescription (uh, okay, it is) and any and all health decisions should be undertaken with that caveat.
One of my criticisms of the book is that she de-emphasizes the inputs of the patient, the diet. I personally feel that the nutrient and energy sources that support the human body are very important. But that is, literally, another book ( or books, tomes, encyclopedias). I understand why the author did not wish to delve into the diet side as there is no consensus on what comprises a healthy diet. I'm not sure there ever will be. Too many personal preferences and belief systems go into dietary choices. Even the timing of meals or doing intermittent fasting has positive effects on longevity. As we have seen in many isolated societies and pre-westernized locations, humans will find a way to thrive and grow with whatever is naturally available to them to eat. I think that is the most important point regarding diet. However you choose to nourish yourself, it should be as close to natural with minimal processing or alteration as possible with a wide variety of foods to get all the nutrients we need to stay healthy, while minimizing toxins from eating too much of the same thing.
Exercise, activity or physical exertion can synergize with these supplements to improve health and longevity. For example, lifting heavy weights stimulates testosterone production and release of growth factors ( or reduces it depending on what paper you are reading. See what I mean about lack of consensus?)
If you have slogged through to this point, here is the bottom line. The author has put together an excellent starting point to help you live longer and healthier lives. The best part is that is accessible to anyone who wishes to try.
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Reviews with images
Fantastic Research and very readable
I want to echo the words of Dr Contrarian. As a physician, I will always advocate that you seek the advice of your health care provider as he/she knows you and your medical problems best. However, in medical school we were not taught very much about supplementation/diet. I have a minor in nutrition and still the systems that Dr Kaufmann discusses were not brought to light during my course of study.I believe the "kaufmann Protocol" is based on sound research and scientific fact. I see patients on many supplements that have questionable proven value that they have been taking on the advice of an "expert" that actually have very little proven clinical or scientific basis.I have been on the protocol for 5 weeks and I can already feel a difference. Of, course incorporating diet and exercise with the protocol, along with a focused effort on taking the Kaufmann Protocol seriously, does obviously make a difference as well.I think if you read this very entertaining book, you will thirst for more. The mobile application for the "Kaufmann protocol" does just that. It is very usable and inspires you to perform every day.The author seems to be very responsive and can break things down into easy to understand advice. She has several speaking engagements in the spring of 2019 and I encourage you to seek these out or encourage the author to post the talks to her website.I think in a few years, she will take over the "Dr Oz's" of the world and provide practical advice to keep us all feeling and looking younger!Buy this book!
Top reviews from the United States
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Reviewed in the United States on April 16, 2018
Reviewed in the United States on December 17, 2018
I believe the "kaufmann Protocol" is based on sound research and scientific fact. I see patients on many supplements that have questionable proven value that they have been taking on the advice of an "expert" that actually have very little proven clinical or scientific basis.
I have been on the protocol for 5 weeks and I can already feel a difference. Of, course incorporating diet and exercise with the protocol, along with a focused effort on taking the Kaufmann Protocol seriously, does obviously make a difference as well.
I think if you read this very entertaining book, you will thirst for more. The mobile application for the "Kaufmann protocol" does just that. It is very usable and inspires you to perform every day.
The author seems to be very responsive and can break things down into easy to understand advice. She has several speaking engagements in the spring of 2019 and I encourage you to seek these out or encourage the author to post the talks to her website.
I think in a few years, she will take over the "Dr Oz's" of the world and provide practical advice to keep us all feeling and looking younger!
Buy this book!
Fantastic Research and very readable
Reviewed in the United States on December 17, 2018
I want to echo the words of Dr Contrarian. As a physician, I will always advocate that you seek the advice of your health care provider as he/she knows you and your medical problems best. However, in medical school we were not taught very much about supplementation/diet. I have a minor in nutrition and still the systems that Dr Kaufmann discusses were not brought to light during my course of study.Reviewed in the United States on December 17, 2018
I believe the "kaufmann Protocol" is based on sound research and scientific fact. I see patients on many supplements that have questionable proven value that they have been taking on the advice of an "expert" that actually have very little proven clinical or scientific basis.
I have been on the protocol for 5 weeks and I can already feel a difference. Of, course incorporating diet and exercise with the protocol, along with a focused effort on taking the Kaufmann Protocol seriously, does obviously make a difference as well.
I think if you read this very entertaining book, you will thirst for more. The mobile application for the "Kaufmann protocol" does just that. It is very usable and inspires you to perform every day.
The author seems to be very responsive and can break things down into easy to understand advice. She has several speaking engagements in the spring of 2019 and I encourage you to seek these out or encourage the author to post the talks to her website.
I think in a few years, she will take over the "Dr Oz's" of the world and provide practical advice to keep us all feeling and looking younger!
Buy this book!
Images in this review
Reviewed in the United States on November 13, 2019
Reviewed in the United States on March 1, 2020
Top reviews from other countries
Daniel Grayling
Perfect book on longevity.
Reviewed in the United Kingdom on July 20, 2023Amazon Kunde
Exzellentes Buch über aktuelle Aging-Forschung + fundierte Supplementierungs-Empfehlungen
Reviewed in Germany on May 14, 2021roberto
Diferenciacion de las celulas, las neuronas reciben, procesan y trasmiten informacion.
Reviewed in Mexico on January 12, 2019
roberto
Reviewed in Mexico on January 12, 2019
Images in this review
Barry Luijbregts
The book is not compatible with my Kindle paperwhite
Reviewed in the Netherlands on February 17, 2019