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Molecular Biology of the Gene 7th Edition

4.3 4.3 out of 5 stars 646 ratings

Now completely up-to-date with the latest research advances, the Seventh Edition of James D. Watson’s classic book, Molecular Biology of the Generetains the distinctive character of earlier editions that has made it the most widely used book in molecular biology. Twenty-two concise chapters, co-authored by six highly distinguished biologists, provide current, authoritative coverage of an exciting, fast-changing discipline.

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About the Author

James D. Watson is Chancellor Emeritus at Cold Spring Harbor Laboratory, where he was previously its Director from 1968 to 1993, President from 1994 to 2003, and Chancellor from 2003 to 2007. He spent his undergraduate years at the University of Chicago and received his Ph.D. in 1950 from Indiana University. Between 1950 and 1953, he did postdoctoral research in Copenhagen and Cambridge, England. While at Cambridge, he began the collaboration that resulted in the elucidation of the double-helical structure of DNA in 1953. (For this discovery, Watson, Francis Crick, and Maurice Wilkins were awarded the Nobel Prize in 1962.) Later in 1953, he went to the California Institute of Technology. He moved to Harvard in 1955, where he taught and did research on RNA synthesis and protein synthesis until 1976. He was the first Director of the National Center for Genome Research of the National Institutes of Health from 1989 to 1992. Dr. Watson was sole author of the first, second, and third editions of Molecular Biology of the Gene, and a co-author of the fourth, fifth and sixth editions. These were published in 1965, 1970, 1976, 1987, 2003, and 2007, respectively. He is also a co-author of two other textbooks: Molecular Biology of the Cell and Recombinant DNA, as well as author of the celebrated 1968 memoir, The Double Helix, which in 2012 was listed by the Library Of Congress as one of the 88 books that shaped America.
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Tania A. Baker is the Head of the Department and Whitehead Professor of Biology at the Massachusetts Institute of Technology, and an Investigator of the Howard Hughes Medical Institute. She received a B.S. in biochemistry from the University of Wisconsin, Madison, and a Ph.D. in biochemistry from Stanford University in 1988. Her graduate research was carried out in the laboratory of Professor Arthur Kornberg and focused on mechanisms of initiation of DNA replication. She did postdoctoral research in the laboratory of Dr. Kiyoshi Mizuuchi at the National Institutes of Health, studying the mechanism and regulation of DNA transposition. Her current research explores mechanisms and regulation of genetic recombination, enzyme-catalyzed protein unfolding, and ATP-dependent protein degradation. Professor Baker received the 2001 Eli Lilly Research Award from the American Society of Microbiology and the 2000 MIT School of Science Teaching Prize for Undergraduate Education and is a fellow of the American Academy of Arts and Sciences since 2004 and was elected to the National Academy of Sciences in 2007. She is co-author (with Arthur Kornberg) of the book DNA Replication, Second Edition.
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Stephen P. Bell is a Professor of Biology at the Massachusetts Institute of Technology and an Investigator of the Howard Hughes Medical Institute. He received B.A. degrees from the Department of Biochemistry, Molecular Biology, and Cell Biology and the Integrated Sciences Program at Northwestern University and a Ph.D. in biochemistry at the University of California, Berkeley in 1991. His graduate research was carried out in the laboratory of Dr. Robert Tjian and focused on eukaryotic transcription. He did postdoctoral research in the laboratory of Dr. Bruce Stillman at Cold Spring Harbor Laboratory, working on the initiation of eukaryotic DNA replication. His current research focuses on the mechanisms controlling the duplication of eukaryotic chromosomes. Professor Bell received the 2001 ASBMB–Schering Plough Scientific Achievement Award, the 1998 Everett Moore Baker Memorial Award for Excellence in Undergraduate Teaching at MIT and the 2006 MIT School of Science Teaching Award.
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Alexander A.F. Gann is the Lita Annenberg Hazen Dean and Professor in the Watson School of Biological Sciences at Cold Spring Harbor Laboratory. He is also a Senior Editor at Cold Spring Harbor Laboratory Press. He received his B.Sc in microbiology from University College London and a Ph.D. in molecular biology from The University of Edinburgh in 1989. His graduate research was carried out in the laboratory of Noreen Murray and focused on DNA recognition by restriction enzymes. He did postdoctoral research in the laboratory of Mark Ptashne at Harvard, working on transcriptional regulation, and that of Jeremy Brockes at the Ludwig Institute of Cancer Research at University College London, where he worked on newt limb regeneration. He was a Lecturer at Lancaster University, U.K., from 1996 to 1999, before moving to Cold Spring Harbor Laboratory. He is co-author (with Mark Ptashne) of the book Genes & Signals (2002), and co-editor (with Jan Witkowski) of The Annotated & Illustrated Double Helix.
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Michael Levine is a Professor of Genetics, Genomics and Development at the University of California, Berkeley, and is also Co-Director of the Center for Integrative Genomics. He received his B.A. from the Department of Genetics at University of California, Berkeley, and his Ph.D. with Alan Garen in the Department of Molecular Biophysics and Biochemistry from Yale University in 1981. As a postdoctoral fellow with Walter Gehring and Gerry Rubin from 1982-1984, he studied the molecular genetics of Drosophila development. Professor Levine's research group currently studies the gene networks responsible for the gastrulation of the Drosophila and Ciona (sea squirt) embryos. He holds the F. Williams Chair in Genetics and Development at University of California, Berkeley. He was awarded the Monsanto Prize in Molecular Biology from the National Academy of Sciences in 1996, and was elected to the American Academy of Arts and Sciences in 1996 and the National Academy of Sciences in 1998.
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Richard M. Losick is the Maria Moors Cabot Professor of Biology, a Harvard College Professor, and a Howard Hughes Medical Institute Professor in the Faculty of Arts & Sciences at Harvard University. He received his A.B. in chemistry at Princeton University and his Ph.D. in biochemistry at the Massachusetts Institute of Technology. Upon completion of his graduate work, Professor Losick was named a Junior Fellow of the Harvard Society of Fellows when he began his studies on RNA polymerase and the regulation of gene transcription in bacteria. Professor Losick is a past Chairman of the Departments of Cellular and Developmental Biology and Molecular and Cellular Biology at Harvard University. He received the Camille and Henry Dreyfuss Teacher-Scholar Award, is a member of the National Academy of Sciences, a Fellow of the American Academy of Arts and Sciences, a Fellow of the American Association for the Advancement of Science, a Fellow of the American Academy of Microbiology, a member of the American Philosophical Society, and a former Visiting Scholar of the Phi Beta Kappa Society. Professor Losick is the 2007 winner of the Selman A. Waksman Award of the National Academy of Sciences, a 2009 winner of the Canada Gairdner Award, and a 2012 winner of the Louisa Gross Horwitz Prize for Biology or Biochemistry of Columbia University.

Product details

  • Publisher ‏ : ‎ Pearson; 7th edition (February 20, 2013)
  • Language ‏ : ‎ English
  • Hardcover ‏ : ‎ 912 pages
  • ISBN-10 ‏ : ‎ 0321762436
  • ISBN-13 ‏ : ‎ 978-0321762436
  • Item Weight ‏ : ‎ 4.87 pounds
  • Dimensions ‏ : ‎ 8.9 x 1.55 x 11.2 inches
  • Customer Reviews:
    4.3 4.3 out of 5 stars 646 ratings

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Customer reviews

4.3 out of 5 stars
4.3 out of 5
646 global ratings
It will get the job done
4 Stars
It will get the job done
This book is in acceptable condition. The pages are all in good condition and legible with a few water marks here and there. My only complaint is that the cover just isn't the prettiest where it hasn't been stored or cared for properly by other users.
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Top reviews from the United States

Reviewed in the United States on September 5, 2015
I bought this book to assist me with my transition into the field of genomics research and molecular biology. I searched around for quite a while looking for a fairly deep and up-to-date books, and I think this book has more than fulfilled this purpose for me. I've been to Cold Springs Harbor Labs (this book is a CSHL Press publication). CSHL's history and place in this field of science is undisputed. Of the authors, I'm taking an online ed.s class from Professor Stephen Bell (MIT), and it is likewise excellent.

What you should expect to find with this book is a text book format, with a quiz after each chapter, and the even questions have answers in the back. The book can easily be read front to back, but is also a very good reference book, with full index.

I've found the book to be very accurate and up-to-date, at least to my level of knowledge. There are very few typographical errors. The figures are plentiful, presented in context, and provide a very good graphical representation of the text they accompany.

I bought the loose leaf version so I could carry around just a few chapters as I read them. This book is nearly 900 pages.
22 people found this helpful
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Reviewed in the United States on May 10, 2019
For my Molecular Genetics Class the Hardcover book was so expensive at my school store and online, yet I only paid $16 for this, and I’ve used it to earn an A in the course! This helped me so much and is REALLY worth the money, I’m amazed I got it for that cheap!
Reviewed in the United States on September 28, 2017
Great! Giving it a 4 star though as the diagrams were in black and white. I had expected them to be in color just as the cover.
Reviewed in the United States on July 24, 2014
As a Molecular Genetics student, this book is a valuable resource. It is packed with information appropriate to any Molecular Biology, Genetics or related course you may encounter. Well written, comprehensive and reasonably priced. And, of course, James Watson (and colleagues) should know what they're talking about, seeing that he and Crick (thanks to Rosalyn Franklin!) made the double helix discovery!
7 people found this helpful
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Reviewed in the United States on March 30, 2021
I didn't really like that it was full of big words. But I liked the small ones
One person found this helpful
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Reviewed in the United States on January 31, 2018
All in black and white. Hard to distinguish the images that required colours to see what they are. Also described as having an access code- which I did not get. Book is fine for studying though.
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3.0 out of 5 stars Book is fine for studying though
Reviewed in the United States on January 31, 2018
All in black and white. Hard to distinguish the images that required colours to see what they are. Also described as having an access code- which I did not get. Book is fine for studying though.
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6 people found this helpful
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Reviewed in the United States on September 21, 2013
Overall, this book is very thorough and clear but not super concise. I would suggest that everyone use it as a reference to go back to whatever is not clear in the lecture.
4 people found this helpful
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Reviewed in the United States on September 9, 2016
Every time I open this book to try and read it or try to use it for homework it finds a new way to disappoint me. The book itself is very informative, but because it is a kindle version it is slow and glitchy. Don't even bother trying to use the search feature or try to skip from page to page, because it will just freeze up and you will lose your place. Even swiping from page to page is terrible. If you try scrolling down it will take forever to load. The text itself is hard to read, and if you try and zoom in, it will distort the pages. The kindle app is terrible, I should have bought my book from chegg instead.
3 people found this helpful
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Top reviews from other countries

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Anchal dalal
5.0 out of 5 stars Recommend it.
Reviewed in India on June 1, 2021
It is definitely worth buying. Even though the book is not colored but the value for this quality of paper is very good. It is a good affordable option.
The book is highly detailed and so many diagrams are shown to understand.
Amazon Customer
5.0 out of 5 stars Excellent Textbook - Essential for any student with goals of graduate studies in Life Sciences.
Reviewed in Canada on June 18, 2018
This is a great textbook. It's very well written. I purchased this text to do some upper level molecular biology before moving on to my Master's degree in Biology. I already had Molecular Biology of the Cell ("big blue") and Essential of Cell Biology in my library, but found they were not detailed enough with regard to what (precisely) is going on throughout genetic expression. This also includes a great detail of structural and biochemical aspects that are not included in most general MB texts. There's a good integration of structural and chemical aspects, with an emphasis on demonstrating function through form (structure), almost like an anatomy and physiology book for molecules. It is fairly detail dense and all of the authors are at the top of the field and current. Included (Ch.7) is a thorough chapter on lab techniques. If that is your focus, Cold Sping Harbor Publications is best. They also have a journal for protocols. If you need more general cell and molecular biology (e.g. vesicle transport, membranes, etc), go with Molecular Bio. of the Cell (Alberts et al.). I wouldn't recommend Essentials of Cell Biology because it's still fairly expensive and doesn't really have anything that isn't included included in MBOC.The only advantage the Essentials would have is being smaller. I was also interested in Molecular Biology: Principles of Genome Function (Craig.N) at the time of purchase. It looked more like an intermediate level of textbook and I couldn't tell if it would have the same detail.
One person found this helpful
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Mathias
5.0 out of 5 stars Molecular Biology de Watson
Reviewed in Mexico on June 27, 2017
Es un clásico y aunque hay otros libros de biología molecular y celular con una visión más integral a nivel de funcionamiento celular, todos aquellos que quieran revisar los principios básicos de la genética molecular pueden disfrutar este texto
angelo manfredini
5.0 out of 5 stars Molecular Biology of the Gene
Reviewed in Italy on December 27, 2018
Io ho la quarta edizione integrale e rileggere alcuni paragrafi aggiornati fa capire l'enormità dei progressi compiuti in questi anni. Questo libro è costato poco più di 20 euro rispetto al mio (in due volumi) pagati centinaia di euro. La copertina è morbida, il libro è pervenuto in ottime condizioni e stampato molto bene. Tutta la stampa è in bianco e nero (la versione integrale porta immagini meglio definite in diversi colori). Do 5 stelle per il rapporto prezzo qualità. Se siete interessati alla biologia molecolare e alla genetica qui siamo ai massimi livelli!!!
One person found this helpful
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信濃豊進
5.0 out of 5 stars my Bible
Reviewed in Japan on January 21, 2021
good people