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Pure Encapsulations P5P 50 - Active Vitamin B6 - Supports Energy Metabolism & Brain Health* - Gluten Free & Non-GMO - 180 Capsules

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4.7 1,821 ratings

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Amazon's Choice in Vitamin B6 Supplements by Pure Encapsulations

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$49.00 $0.27 per Count

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Purchase options and add-ons

Brand	Pure Encapsulations
Item Form	Capsule
Primary Supplement Type	Vitamin-b
Diet Type	Gluten Free
Flavor	Unflavored

About this item

Activated Vitamin B6: Pure Encapsulations P5P 50, an active vitamin B6 dietary supplement form, supports energy metabolism, heart, and brain health*
Energy Metabolic Support: Activated vitamin B6 facilitates the release of glycogen used in energy production; balances body fluids*
Immune Health Aid: Easy-to-swallow capsules support the production of antibodies and red blood cells*
Suggested Use: As a dietary supplement, take 1 non-GMO, gluten free capsule, 1-2 times daily, with meals
Pure Difference: What we leave out matters, too; Pure Encapsulations products are FREE FROM common allergens, artificial or unnecessary ingredients, and GMOs

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From the brand

How did we get our start?

We’ve spent the last 30 years researching, innovating, and developing our comprehensive line of premium supplements to bring you over 400 uniquely formulated products.

What makes our products unique?

What makes us different is the promise of goodness that goes into every one of our supplements - tested to ensure they are FREE FROM unnecessary additives and many common allergens.

Why do we love what we do?

We’re dedicated to providing nutritional supplements that are designed with integrity, backed by verifiable science, and held to the highest industry standards.

Sustainability features

This product has sustainability features recognized by trusted certifications.

Packaging efficiency

Reduced air and/or water in the product or packaging for more efficient transportation.

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Compact by Design (Amazon-developed Certification)

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Climate Pledge Friendly

Product Description


The Truest Quality What makes us different is the promise of goodness that goes into every one of our supplements. We take high standards seriously, which is why we're the #1 most recommended professional supplement brand, ranked highest in quality and trust.^ ^Among professional supplement brands surveyed, Nutrition Business Journal 2016, 2020, 2023.	Good from Start to Finish When developing our products, we work in close collaboration with leading medical professionals and nutritional experts to create premium dietary supplements that you can feel good about. Our high-quality ingredients are backed by science with many of our formulations being included in more than 50 product-specific clinical studies in leading peer-reviewed journals. FDA Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.	Goodness at our Core Pure Encapsulations was built with the purest of hearts and a plan to improve the wellness and wellbeing of others. This heartfelt commitment now extends to the planet as we move forward in sustainability initiatives and continue to support incredible organizations dedicated to leading the charge for a greener future.

Focus on sustainability

Compact by design from Climate pledge friendly. Certified by Amazon.

Small changes in product size & weight lead to lower carbon emissions.

We created Compact by Design to identify products that, while they may not always look very different, have a more efficient design. With the removal of excess air and water, products require less packaging and become more efficient to ship. At scale, these small differences in product size and weight lead to significant carbon emission reductions.

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Product details

Is Discontinued By Manufacturer ‏ : ‎ No
Product Dimensions ‏ : ‎ 3.39 x 1.97 x 1.89 inches; 1.6 ounces
Department ‏ : ‎ unisex-adult
Date First Available ‏ : ‎ July 3, 2008
Manufacturer ‏ : ‎ Pure Encapsulations
ASIN ‏ : ‎ B001WUTBBQ

Best Sellers Rank: #10,273 in Health & Household (See Top 100 in Health & Household)
- #8 in Vitamin B6 Supplements
- #989 in Diet & Sports Nutrition
- #1,009 in Climate Pledge Friendly: Health and Household

Customer Reviews:
4.7 1,821 ratings

Compare with similar items

	This Item Pure Encapsulations P5P 50 - Active Vitamin B6 - Supports Energy Metabolism & Brain Health* - Gluten Free & Non-GMO - 180 Capsules	Recommendations Nutricost P5P Vitamin B6 Supplement 50mg, 240 Capsules (Pyridoxal-5-Phosphate) - Vegetarian Friendly, Non-GMO, Gluten Free	dummy Nutricost P5P Vitamin B6 Supplement 100mg, 240 Capsules (Pyridoxal-5-Phosphate) - Vegetarian Friendly, Non-GMO, Gluten Free	dummy Jarrow Formulas Extra Strength Methyl B-12 1000 mcg & Methyl Folate 400 mcg + P-5-P, Dietary Supplement for Cellular Energy Metabolism and Cardiovascular Support, 100 Chewable Tablets, 100 Day Supply	dummy Renzo's Bright & Brainy Vitamin B6 - Dissolving Kids Vitamin B6-60 Sugar-Free Melty Tabs, Oh Oh Oh Orange Flavored	dummy Super B-Complex – Methylated Sustained Release Clean Label B Complex with Methylfolate, Boosted B12 Methylcobalamin, Vegan, Lab Verified, 60 Small Tablets, by Igennus
	Try again! Details Added to Cart	Try again! Details Added to Cart	Try again! Details Added to Cart	Try again! Details Added to Cart	Try again! Details Added to Cart	Try again! Details Added to Cart
Price	$49.00	-26% $16.95 List: $22.95	-31% $21.95 List: $31.95	-20% $17.24 List: $21.50	$16.99	-15% $12.65 List: $14.95
Price Per Unit	$0.27 / Count	$0.07 / Count	$0.09 / Count	$0.17 / Count	$0.28 / Count	$0.21 / Count
Delivery	Get it as soon as Tuesday, May 14	Get it as soon as Tuesday, May 14	Get it as soon as Tuesday, May 14	Get it as soon as Tuesday, May 14	Get it as soon as Tuesday, May 14	Get it as soon as Tuesday, May 14
Customer Ratings	4.71,821	4.6522	4.7459	4.66,852	4.51,927	4.622,248
Easy to swallow	4.9	4.4	4.9	4.5	3.8	4.7
Flavor	4.7	4.1	4.7	4.3	3.7	4.1
Value for money	4.7	4.3	4.7	4.5	4.0	4.6
Sold By	Pattern.	eSupplements	eSupplements	Amazon.com	Renzo's Vitamins	Amazon.com
primary supplement	Vitamin-b	Vitamin B6	Vitamin-b	Vitamin B12, Vitamin B6, Vitamin B9	Vitamin-b	B-Complex
form	Capsule	Capsule	Capsule	Tablet	Tablet	Tablet
unit count	180	240	240	100	60	60
flavor	Unflavored	Unflavored	Unflavored	Lemon	Orange	Unflavored
target gender	unisex	unisex	unisex	unisex	unisex	unisex
weight	0.1 pounds	50 milligrams	0.33 pounds	0.2 pounds	0.63 ounces	19 grams
specific uses	Nerve	—	—	Metabolism, Energy	Nerve	Immune Support
serving suggestion	1 capsule	1 capsule	1 capsule	1 lozenge per serving	1 tablet	Adults should take 1 Super B-Complex tablet twice daily with food. Children aged 7-16 years should take 1 tablet daily

Important information

Safety Information

If you are pregnant or lactating, have any health condition or are taking any medication, consult your health professional before use.

Indications

Pure Encapsulations - P-5-P 50 - 180's

Ingredients

Each serving size (1 vegetarian capsule) contains: Vitamin B6 (as pyridoxal 5' phosphate) (activated B6) 50 mg. Other ingredients: Hypoallergenic plant fiber (cellulose), vegetarian capsule (cellulose, water), ascorbyl palmitate.

Directions

As a dietary supplement, take 1 capsule, 1-2 times daily, with meals.

Legal Disclaimer

*These statements have not been evaluated by the Food & Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Please contact your healthcare professional immediately if you experience any unwanted side effects. The information contained herein is for informational purposes only and does not establish a doctor-patient relationship. Please be sure to consult your physician before taking this or any other product. †All Pure Encapsulations ingredients, including those derived from corn, are GMO free. We obtain statements from each of our suppliers certifying that the ingredients do not contain GMOs. For some nutrients, we conduct PCR testing to confirm the absence of genetically modified material.

Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease or health condition.

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Customer reviews

4.7 out of 5

1,821 global ratings

How customer reviews and ratings work

Customers say

Customers like the small size, quality and ease of swallowing of the vitamin. They mention that it's powerful, easy to take and helps with anxiety and morning sickness. Customers also say it'll help you sleep better all night.

AI-generated from the text of customer reviews

101 customers mention101 positive0 negative

Customers are satisfied with the quality of the vitamin. They mention that it is a great product, it has high quality safe ingredients, and it does the job perfectly. Some say that the brand is excellent and that it provides great health benefits of vitamin B6.

"...They actually make me more calm!! It’s wonderful! I’m thinking of trying more activated B vitamins now because these have worked so well!" Read more

"Was recommended by a functional doctor. Definitely helps with energy levels! Great quality product and affordable." Read more

"...All two-piece capsules are hypoallergenic and vegetarian." Read more

"...I am hoping it improves my energy as well. I also remembered my dreams for the first time in years (another potential symptom of pyroluria)...." Read more

33 customers mention26 positive7 negative

Customers like the effect of the vitamin on mood. They say it has almost completely relieved all their symptoms, helps tremendously for the anxiety side effect of new seizure medication, significantly reduces morning sickness, and helps with sleep. Some say it's amazing for their energy and depression, and makes them more calm. They also mention that it helps with tendonitis and inflammation, and works with healing neurological injuries in conjunction with B6.

"...It helps tremendously for the anxiety side effect of the new seizure medication. I plan to take it permanently. It really helps with mood!" Read more

"...They actually make me more calm!! It’s wonderful! I’m thinking of trying more activated B vitamins now because these have worked so well!" Read more

"...In only 1 week my hand pain began dissappearing, in 3 weeks they were no longer locking up with simple use...." Read more

"Most vitamins make me have some nausea, this one is great, I don’t get side effects." Read more

17 customers mention17 positive0 negative

Customers find the vitamin easy to swallow. They say it's made to be easy on the body, tummy, and feels great taking it. They also say it helps restore full range of pain-free movement and is much more easily absorbed than tablet form.

"...These are small capsules so they are easy to swallow...." Read more

"...But I can take these and my body feels so good on them! They actually make me more calm!! It’s wonderful!..." Read more

"...small, easy to swallow capsulesWhat Is The Source?Pure Encapsulations P5P50 is synthetically derived...." Read more

"...It is a good quality product and was easy to take!" Read more

5 customers mention5 positive0 negative

Customers appreciate the small capsule size of the vitamin. They say there isn't very much filler and the capsules are easy to swallow.

"...These are small capsules so they are easy to swallow...." Read more

"...You can tell because the capsules are so small- there isn't very much filler...." Read more

"Trusted brand, small capsules-easy to swallow. Good quality overall" Read more

"Perfect size!" Read more

5 customers mention0 positive5 negative

Customers are dissatisfied with the pain relief of the vitamin. They mention that it makes their stomach hurt, makes them nauseous, and causes their face to breakout. Some customers also report that the vitamin makes them vomit within an hour.

"...I get a sharp pain in my stomach within minutes and then stomach problems for another hour or so. 25 mg once or twice a day might be better for me...." Read more

"...a few days of taking them I started developing dry, super itchy patches on my chest, stomach, and arms. It also made my face breakout very badly...." Read more

"...was making me sick since it was the only change and I was throwing up within an hour and was sick the rest of the day...." Read more

"...I took my first dose and within 45 minutes because very nauseous and vomited within an hour and off and on for a couple hours after that...." Read more

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sophiesmom

Very Good Quality.

Reviewed in the United States on May 10, 2023

Size: 60 Count (Pack of 1)Verified Purchase

I have to take a minimum of 100mg a day. Some days I need to take 150-200mg a day so I like this strength. I have found a cheaper brand that I will try in order to save money. If it doesn’t work for me I will go back to this brand. I have to take the P5P version of B6 in order to be able to absorb the vitamin. These are small capsules so they are easy to swallow. This was recommended by my neurologist to use for 3 months during a seizure medication change. It helps tremendously for the anxiety side effect of the new seizure medication. I plan to take it permanently. It really helps with mood!

27 people found this helpful

Helpful

Life changing

Reviewed in the United States on June 24, 2023

Size: 60 Count (Pack of 1)Verified Purchase

I have this weird reaction that I’ve never heard of anyone else having to classic B vitamins. If I take any of them, they make me really angry within a short time. It’s very unusual. So I haven’t been able to take them for many years. But I can take these and my body feels so good on them! They actually make me more calm!! It’s wonderful! I’m thinking of trying more activated B vitamins now because these have worked so well!

44 people found this helpful

Helpful

Townsend

Great quality

Reviewed in the United States on November 8, 2023

Size: 60 Count (Pack of 1)Verified Purchase

Was recommended by a functional doctor. Definitely helps with energy levels! Great quality product and affordable.

4 people found this helpful

Helpful

Jeanine S

pyridoxal 5' phosphate (activated B6 )

Reviewed in the United States on July 10, 2014

Verified Purchase

EACH CAPSULE CONTAINS:
pyridoxal 5' phosphate (activated B6 ) 50 mg
ascorbyl palmitate (fat soluble vitamin C) 3 mg
other ingredients: hypo-allergenic plant fiber (cellulose, vegetarian capsule (cellulose, water
small, easy to swallow capsules

What Is The Source?
Pure Encapsulations P5P50 is synthetically derived. Vitamin C (ascorbyl palmitate) is derived from corn dextrose fermentation and palm oil. Hypo-allergenic plant fiber is derived from pine cellulose.

The capsules are made from Southern Pine, grown in the US. The pine is pesticide free. The hypo-allergenic plant fiber Pure Encapsulations uses is a pharmaceutical grade alpha cellulose derived from purified specialty grades of wood pulp from Southern pine. Due to the nature of the raw material (wood pulp) and the manufacturing process, it does not contain alcohol, grain, corn, corn starch, sulfa, sulfites, animal products or gluten. In addition, it is free of pesiticides and heavy metals. There are no known allergens in this plant fiber.

All ingredients in Pure Encapsulations products are non-GMO.

High risk ingredients have been tested for the presence of genetically modified material.

Comprehensive Allergen SOP in place to prevent cross-contamination.

Pure Encapsulations does not add coatings, binders, fillers, excipients, artificial flavors, artificial sweeteners or colors.
Pure Encapsulations does not use magnesium stearate in any of their products.

All two-piece capsules are hypoallergenic and vegetarian.

82 people found this helpful

Helpful

Texas Lark

Good for a B6 Deficiency, but This is a Large Dose to Take

Reviewed in the United States on June 2, 2017

Size: 180 Count (Pack of 1)Verified Purchase

Great supplement for those suffering from B6 deficiency, especially due to pyroluria. I immediately felt more alert after taking this (within 15 minutes). I've been having trouble with short-term memory and this seems to be helping. I am hoping it improves my energy as well. I also remembered my dreams for the first time in years (another potential symptom of pyroluria). However, I think 50 mg is too much for me to take at once. I get a sharp pain in my stomach within minutes and then stomach problems for another hour or so. 25 mg once or twice a day might be better for me. If you have a sensitive stomach, beware. Definitely take it with a meal and consider a smaller dose if you have side effects.. And from another family member's experience, some people cannot tolerate a lot of P5P, even when they need it. In that case, start low and go slow.

41 people found this helpful

Helpful

Sean Regan

P5P is great for optimizing nutrition, superior to vitamin B6, and this is an excellent brand

Reviewed in the United States on February 18, 2014

Verified Purchase

I bought this to take along with other supplements that I use for enhancing my workouts. I take P5P with L-tyrosine, L-theanine, Taurine and branched chain amino acids before my workouts. I notice a significant difference when taking my supplements before working out, and I notice even more of a difference when I take P5P instead of vitamin B6.

Vitamin B6 is necessary for cell utilization of nutrients (especially amino acids). P5P is the reduced form of B6, it does not require any dietary cofactors to be used by the body. This makes it more useful when you take it on an empty stomach, which I do, because amino acid supplements are best taken on an empty stomach.

Specific to this product: Pure Encapsulations is a premium brand. Hence the premium price. But in my book, its worth it. The products are really high quality; I take a Pure multivitamin, recommended by my naturopath, and the ingredients are superior to any other that I've had. This P5P is high potency, high dose, and high purity. You can tell because the capsules are so small- there isn't very much filler. The shipping was reasonable and the bottle was in fine shape when I received it, didn't look tampered with or damaged (which is important when buying medications and supplements online)

116 people found this helpful

Helpful

H. R.

Great Quality and Value

Reviewed in the United States on May 29, 2023

Size: 60 Count (Pack of 1)Verified Purchase

No chemical additives or fillers. Good supplement

5 people found this helpful

Helpful

Red Dog

Stops trigger finger!

Reviewed in the United States on August 25, 2018

Verified Purchase

After finding out activated p5p cures trigger finger I decided to give it a shot. My hands were just short of being totally incapacitated by pain and inability to bend my fingers without them locking into the bent position. I'm 59 and an engineer. My hands are crucial to my livelyhood. I started taking 2 in the morning and 2 at night. In only 1 week my hand pain began dissappearing, in 3 weeks they were no longer locking up with simple use. Now I'm over a month and they haven't locked up a bit even with heavy gripping and mechanical use. I lived with pain for over a year, now only a month later I have full use again. Love this stuff. Non toxic and does the job perfectly!

153 people found this helpful

Helpful

Disclaimer: While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. Actual product packaging and materials may contain more and/or different information than that shown on our Web site. We recommend that you do not solely rely on the information presented and that you always read labels, warnings, and directions before using or consuming a product. For additional information about a product, please contact the manufacturer. Content on this site is for reference purposes and is not intended to substitute for advice given by a physician, pharmacist, or other licensed health-care professional. You should not use this information as self-diagnosis or for treating a health problem or disease. Contact your health-care provider immediately if you suspect that you have a medical problem. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease or health condition. Amazon.com assumes no liability for inaccuracies or misstatements about products.

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Pure Encapsulations P5P 50 - Active Vitamin B6 - Supports Energy Metabolism & Brain Health* - Gluten Free & Non-GMO - 180 Capsules

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PRODUCT CERTIFICATION (1)

PRODUCT CERTIFICATION (1)

From the brand

How did we get our start?

What makes our products unique?

Why do we love what we do?

Sustainability features

Product Description

The Truest Quality

Good from Start to Finish

Goodness at our Core

Focus on sustainability

Small changes in product size & weight lead to lower carbon emissions.

Here are a few of the many ways products can qualify:

Product details

Compare with similar items

Videos

Videos for this product

About Pure Encapsulations

Important information

Safety Information

Indications

Ingredients

Directions

Legal Disclaimer

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Customer reviews

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